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Since July 2001      Working at Division of Neurology, Department                            Genetics of Parkinson’s disease:

                               of Medicine, Faculty of Medicine, Ramathibodi                            why should we know about it?
                               Hospital, Mahidol University, Bangkok
          – Jul 2001-Feb 2004   Lecturer                                                                         Teeratorn Pulkes, MD, PhD, FRCP, FRCP(T)

          – Mar 2004-Sep 2013   Associate Professor                                                                    Division of Neurology, Department of Medicine,
          – Sep 2013-current   Professor in Neurology                                                                      Faculty of Medicine, Ramathibodi Hospital,

          – Jul 2015-current   –  Deputy Head of Department for Research,                                                                     Mahidol University
                                  Department of Medicine
                               – Committee member, the ethical committee

                                  on the human rights related to research
                                  involving human subjects, Ramathibodi                          During the past 20 years, technologies of molecular genetics have
                                  Hospital                                                  advanced dramatically, resulting in discoveries of mutations and genetic

                               – Committee member, the Ramathibodi Hospital                 risk variants in numerous newly identified genes associated with common
                                  Research Fund                                             non-communicable diseases; diabetes mellitus is one notable example of
                               – Review subcommittee of the application for                 this. Regarding neurological diseases, Parkinson’s disease (PD) is an

                                  the academic position, Faculty of Medicine,               important example, where the genetic variants have an odd ratio ranging
                                  Ramathibodi Hospital                                      from a small association of two to a very strong association of thirty. The

          – Jan 2017-current   Head of Division of Neurology                                identification of relevant genetic risk alleles gives us a better understanding
                                                                                            of the molecular pathogenesis of PD, which opens the way to discover

                                                                                            treatment of these incurable diseases. Since PD patients almost invariably
                                                                                            exhibit clinical symptoms several years after the pathological process in
                                                                                            the nervous system commenced, it is necessary to get early diagnosis in

                                                                                            order to treat these patients at a very early stage. Theoretically, known
                                                                                            genetic variants associated with PD should be one of the good candidates

                                                                                            using for detecting persons at risk of PD.



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