Page 19 - ไฟล์ อรรถสิทธิ์
P. 19
Unfortunately, causative genetic mutations and risk variants of
neurogenetic diseases appear to vary widely amongst different ethnic NOTE
groups, which makes existing research data on PD genetics based on one
population often inapplicable for the others. In particular, risk alleles of
PD are shown to be different even in ethnicities with geographically close
proximity such as Thais compared to Chinese. This variation leads to
different tools necessary in screening early stage patients. Thus, pinpointing
risk alleles in Thai population can result in significantly improved
preventative measures for PD in a cost-effective way.
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