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Since July 2001 Working at Division of Neurology, Department Genetics of Parkinson’s disease:
of Medicine, Faculty of Medicine, Ramathibodi why should we know about it?
Hospital, Mahidol University, Bangkok
– Jul 2001-Feb 2004 Lecturer Teeratorn Pulkes, MD, PhD, FRCP, FRCP(T)
– Mar 2004-Sep 2013 Associate Professor Division of Neurology, Department of Medicine,
– Sep 2013-current Professor in Neurology Faculty of Medicine, Ramathibodi Hospital,
– Jul 2015-current – Deputy Head of Department for Research, Mahidol University
Department of Medicine
– Committee member, the ethical committee
on the human rights related to research
involving human subjects, Ramathibodi During the past 20 years, technologies of molecular genetics have
Hospital advanced dramatically, resulting in discoveries of mutations and genetic
– Committee member, the Ramathibodi Hospital risk variants in numerous newly identified genes associated with common
Research Fund non-communicable diseases; diabetes mellitus is one notable example of
– Review subcommittee of the application for this. Regarding neurological diseases, Parkinson’s disease (PD) is an
the academic position, Faculty of Medicine, important example, where the genetic variants have an odd ratio ranging
Ramathibodi Hospital from a small association of two to a very strong association of thirty. The
– Jan 2017-current Head of Division of Neurology identification of relevant genetic risk alleles gives us a better understanding
of the molecular pathogenesis of PD, which opens the way to discover
treatment of these incurable diseases. Since PD patients almost invariably
exhibit clinical symptoms several years after the pathological process in
the nervous system commenced, it is necessary to get early diagnosis in
order to treat these patients at a very early stage. Theoretically, known
genetic variants associated with PD should be one of the good candidates
using for detecting persons at risk of PD.
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