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Since July 2001   Working at Division of Neurology, Department   Genetics of Parkinson’s disease:

 of Medicine, Faculty of Medicine, Ramathibodi   why should we know about it?
 Hospital, Mahidol University, Bangkok
 – Jul 2001-Feb 2004   Lecturer  Teeratorn Pulkes, MD, PhD, FRCP, FRCP(T)

 – Mar 2004-Sep 2013   Associate Professor  Division of Neurology, Department of Medicine,
 – Sep 2013-current   Professor in Neurology  Faculty of Medicine, Ramathibodi Hospital,

 – Jul 2015-current   –  Deputy Head of Department for Research,  Mahidol University
 Department of Medicine
 – Committee member, the ethical committee

 on the human rights related to research
 involving human subjects, Ramathibodi     During the past 20 years, technologies of molecular genetics have
 Hospital  advanced dramatically, resulting in discoveries of mutations and genetic

 – Committee member, the Ramathibodi Hospital  risk variants in numerous newly identified genes associated with common
 Research Fund  non-communicable diseases; diabetes mellitus is one notable example of
 – Review subcommittee of the application for  this. Regarding neurological diseases, Parkinson’s disease (PD) is an

 the academic position, Faculty of Medicine,  important example, where the genetic variants have an odd ratio ranging
 Ramathibodi Hospital  from a small association of two to a very strong association of thirty. The

 – Jan 2017-current   Head of Division of Neurology  identification of relevant genetic risk alleles gives us a better understanding
          of the molecular pathogenesis of PD, which opens the way to discover

          treatment of these incurable diseases. Since PD patients almost invariably
          exhibit clinical symptoms several years after the pathological process in
          the nervous system commenced, it is necessary to get early diagnosis in

          order to treat these patients at a very early stage. Theoretically, known
          genetic variants associated with PD should be one of the good candidates

          using for detecting persons at risk of PD.



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